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ea0026p735 | Diabetes (epidemiology, pathophysiology) | ECE2011

Insulin restores salivary secretion in diabetic rats: involvement of Na+/glucose cotransporter SGLT1

Sabino-Silva R , Campello R S , Nakamura H K , Freitas H S , Okamoto M M , Mori R C , Machado U F

Introduction: Considering the high capacity of water transport of Na+/glucose cotransporter SGLT1, the aim of this study was to investigate the potential role the SGLT1 in luminal membrane of ductal cells of salivary glands upon the non-stimulated salivary secretion of diabetic rats. The present study also investigates the presence of glucose transporter GLUT1 in salivary glands of rats.Methods: Non-stimulated salivary secretion and SGLT1/GLUT1 protein (...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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